Epothilone B

• Description :

  A macrolide anticancer agent. Similar to paclitaxel (Cat. No. 1567-25), epothilone B induces microtubule polymerization and stabilizes microtubules against depolymerization conditions. In addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing P-glycoprotein, a characteristic that distinguishes it from the taxanes. Also induces G2-M cell cycle arrest (EC₅₀= 3 - 92 nM).

• Shipping Conditions :

  gel pack

• Storage Conditions :

  -20°C

• Shelf Life :

  24months