Products for Research Use Only

GYY 4137

CAT: 0026-1908-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-1908-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A slow-releasing, water-soluble hydrogen sulfide (H₂S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months