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Rocaglamide

CAT: 0026-1863-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0026-1863-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
An immunosuppressant and a potent inhibitor of NF-κB activation in T cells, with an almost complete inhibition at 200 nM. Suppresses cytokine production (IFN-γ, TNF-α, IL-2 and IL-4) and inhibits NF-AT in peripheral blood T cells at concentrations that do not impair NF-κB and AP-1 activities. Also induces mitochondria-mediated apoptosis in leukemia cells and sensitizes CD95/CD95L-mediated apoptosis in malignant T-cells by differential regulation of CD95L and c-FLIP expression.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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