SU 1498

CAT: 0026-1836-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-1836-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent and selective inhibitor (IC₅₀ = 700 nM) of vascular endothelial growth factor receptor 2 (VEGFR 2) (also known as Flk1). Very weak inhibitor of PDGFR-kinase (IC₅₀ >50 µM), EGFR-kinase (IC₅₀ >100 µM)and HER-2 kinase (IC₅₀>100 µM). SU1498 has been shown to cause accumulation of phosphorylated ERK and inhibits its activity in vivo and in vitro by inhibition of ERK dephosphorylation.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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