Bafilomycin A1

Bafilomycin A1

• Description: A highly potent and selective inhibitor of vacuolar H⁺-ATPases (V-ATPases) in vitro. It is effective in nanomolar concentrations in animal cells, plant cells and microorganisms; also selective over other ATP hydrolyzing enzymes such as F-ATPases, Ca²⁺-ATPases, Na⁺/K⁺-ATPases and plasma membrane H⁺-ATPases. Also prevents autophagy at a late stage by inhibiting fusion between autophagosomes and lysosomes.
• Shipping Conditions: gel pack
• Storage Conditions: -20°C
• Shelf Life: 24 months