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Rottlerin

CAT: 0026-1827-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-1827-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Originally reported as an inhibitor of Protein Kinase C isoforms with selectivity for PKCδ. However, more recent studies have shown Rottlerin did not block PKCδ activity but did block other kinase and non-kinase proteins in vitro and activated multiple Ca²⁺-sensitive K⁺ channels with high potency. It uncouples mitochondria and affects mitochondrial production of reactive oxygen species (ROS). Also induces autophagy through inhibition of mTORC1.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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CatalogName
T16791-01Rottlerin

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