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FK-506

CAT: 0026-1563-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-1563-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent immunosuppresant and in vitro T cell proliferation blocker. It disrupts calcineurin-mediated signal transduction in T-lymphocytes. It interacts with its FK506-binding protein-12 (FKBP-12), leading to increase in the release of sarcoplamic reticulum-derived calcium. FK506 and rapamycin, but not cytosporin inhibit aldosterone-stimulated sodium transport in A6 cells.
Shipping Conditions
RT
Storage Conditions
-20°C
Shelf Life
24months

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