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Calmodulin-Sepharose Beads

CAT: 0026-7934-5Size: 5 mLDry Ice: NoHazardous: No
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CAT#:0026-7934-5Size:5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Calmodulin is a highly conserved regulatory eukaryotic protein involved in various cellular processes such as glycogen metabolism, cytoskeletal control, neurotransmission, phosphate activity and control of NAD/NADP. The diverse functions of calmodulin rely on its ability to interact with, and regulate the activities of large number of its target proteins/enzymes. Calmodulin binds proteins usually through its hydrophobic sites, which are exposed due to conformational changes in the presence of Ca2+. However, some target proteins interact with Calmodulin in a calcium-independent manner. Calmodulin-Sepharose beads allow for specific enrichment of known or unknown calmodulin-binding proteins from biological samples. In addition, Calmodulin-Sepharose beads provide a convenient tool for affinity purification of calmodulin binding peptide (CBP) tagged recombinant proteins. Elution of CBP tagged proteins could be achieved by simply adding chelation ligand / removing Ca2+.
Shipping Conditions
gel pack
Storage Conditions
+4°C
Shelf Life
12 months

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