Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
RP-4025-01	Myeloperoxidase (MPO)
RP-4025-02	Myeloperoxidase (MPO)
GWB-F3E6F2	Myeloperoxidase (MPO)
MBS641141-02	MPO, CT (MPO, Myeloperoxidase, 89kD myeloperoxidase, 84kD myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain)
MBS641141-01	MPO, CT (MPO, Myeloperoxidase, 89kD myeloperoxidase, 84kD myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain)
R30233	Myeloperoxidase Antibody / MPO
FY-AB48938-02	Anti-Myeloperoxidase (MPO)
FY-AB48939-01	Anti-Myeloperoxidase (MPO)
SIPA246Hu01-05	Recombinant Myeloperoxidase (MPO)
SIPA246Ra01-05	Recombinant Myeloperoxidase (MPO)

CAT:

26-K746-200

Size:

200 Assays

Price:

Ask

For price, please contact [email protected].

Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric)

Description: Myeloperoxidase (MPO: EC 1.11.2.2) is a peroxidase abundantly expressed in neutrophil granulocytes. It catalyzes the hydrogen peroxide dependent oxidation of halide ions to generate hypochlorite (HClO), the reaction by which MPO exhibits cytotoxic activity against tumor cells and microorganisms. MPO also oxidizes various substances such as phenol and anilines. MPO undergoes chlorination or peroxidation reaction depending upon the relative concentrations of chloride and the reducing substrates. Recent studies suggest that increased levels of MPO are associated with an increased risk for cardiovascular disease and myocardial infarction, thus development of novel and specific inhibitors of MPO is critical for therapeutic purposes. BioVision’s MPO Inhibitor Screening Kit provides screening assays for both MPO chlorination and peroxidation activities. In the chlorination assay (specific for MPO), MPO converts hydrogen peroxide and sodium chloride to sodium hypochlorite, which reacts with Chlorination substrate to give an intensely fluorescent product (Ex/Em = 480/520 nm). In the Peroxidation Assay, MPO oxidizes peroxidation substrate to generate fluorescence (Ex/Em = 535/587 nm). The fluorescence generated is directly proportional to any peroxidase activity present. In the presence of MPO inhibitor, reactions are impeded, thus decreasing the rate and/or extent of generation of MPO-dependent fluorescence. This kit provides a sensitive, quick, and easy method for screening potential inhibitors of MPO, and identifying whether one or both activities are inhibited. MPO Inhibitor Control is included to compare the efficacy of test inhibitors. The assay is high-throughput adaptable and can be performed in less than 20 min.
Applications: Screening/characterizing/studying potential inhibitors of MPO
Detection Method: Fluorescence (Ex/Em 535/587 nm)
Features & Benefits: • Rapid and simple • Reliable test for screening potential inhibitors of MPO • Includes Inhibitor Control [4-Aminobenzonic Hydrazide]
Shipping Conditions: gel pack
Storage Conditions: -20°C
Shelf Life: 12 months

Complementary Product Range

Our range of products, including Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
K746-200	Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric)
3831-100	Myeloperoxidase (MPO) Antibody
3831-30T	Myeloperoxidase (MPO) Antibody
3831BP-50	Myeloperoxidase (MPO) Blocking Peptide
1977-100	Myeloperoxidase Inhibitor
E4579-100	Myeloperoxidase (MPO) (Human) ELISA Kit
E4580-100	Myeloperoxidase (MPO) (Mouse) ELISA Kit
E4581-100	Myeloperoxidase (MPO) (Rat) ELISA Kit
1977-500	Myeloperoxidase Inhibitor
K747-100	Myeloperoxidase (MPO) Peroxidation Activity Assay Kit