PicoProbe™ Fructose-1,6-Bisphosphatase Inhibitor Screening Kit (F)
CAT:
26-K399-100
Size:
100 Assays
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PicoProbe™ Fructose-1,6-Bisphosphatase Inhibitor Screening Kit (F)
- Description: Fructose-1,6-bispohphatase (FBP1) is responsible for the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in the rate determining step of gluconeogenesis. FBP1 is a tetramer that plays a role in regulating adiposity and appetite. FBP1 has emerged as an important therapeutic target to treat diabetes type 2 to regulate glucose levels during gluconeogenesis. In BioVision’s FBP1 Inhibitor Screening Kit, human FBP1 hydrolyzes fructose-1,6-bisphosphate to fructose-6-phosphate which oxidizes and reacts with a fluorogenic probe, that is detected at Ex/Em= 535/587 nm. The assay is fast, sensitive, high-throughput compatible and provides a quick and sensitive way for screening, studying and characterizing potential novel inhibitors of FBP1
- Reactivity: Human
- Applications: Screening/characterizing/studying FBP1 inhibitors/activators
- Detection Method: (Ex/Em= 535/587 nm)
- Features & Benefits: • Simple and reliable test to screen FBP1 inhibitors/activators • High-throughput compatible • Includes Inhibitor Control (AMP)
- Shipping Conditions: gel pack
- Storage Conditions: -20°C
- Shelf Life: 12 months