Succinate Dehydrogenase (SDH) (Rat) ELISA Kit
CAT:
26-E4596-100
Size:
100 Assays
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Succinate Dehydrogenase (SDH) (Rat) ELISA Kit
- Description: Succinate Dehydrogenase (SDH) or succinate-coenzyme Q reductase (SQR) or respiratory complex II is an enzyme complex, which is bound to the inner mitochondrial membrane. SDH participates in both the citric acid cycle and electron transport chain. In mammals and many bacteria, SDH consists of 2 hydrophilic subunits, SDHA (flavoprotein) and SDHB (iron-sulfur protein) and 2 hydrophobic membrane anchor subunits: SDHC and SDHD. SDH oxidizes succinate to fumarate and transfers the electrons to ubiquinone. SDH deficiency in humans leads to a variety of phenotypes including Leigh syndrome, a neurometabolic disorder, tumor formation, and myopathy. Recent studies show that SDH can prevent the generation of ROS (reactive oxygen species); therefore, measurement of succinate dehydrogenase activity has wide applications. BioVision’s Succinate Dehydrogenase ELISA kit is a sandwich ELISA assay for the quantitative measurement of SDH in Rat serum, plasma and cell culture supernatants. The density of color is proportional to the amount of SDH captured from the samples.
- CAS Number: 7732-18-5
- Reactivity: Rat
- Applications: This ELISA kit is used for quantitative measurement of Succinate Dehydrogenase in rat serum, plasma, tissue homogenates and other biological fluids.
- Detection Method: Absorbance (450 nm)
- Features & Benefits: Easy, convenient and time-saving method to measure the level of Succinate Dehydrogenase in serum, plasma, tissue homogenates, culture supernatants and other biological fluids. Detection Range: 0.313 - 20 ng/ml Sensitivity: < 0.188 ng/ml Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10% No significant cross-reactivity or interference was observed.
- Shipping Conditions: gel pack
- Storage Conditions: 4°C
- Shelf Life: 12 months