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JJH260

CAT: 0804-HY-116895-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-116895-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JJH260 is AIG1inhibitor, and inhibit the fluorophosphonate reactivity and fatty acid esters of hydroxy fatty acid (FAHFA) hydrolysis activity of AIG1in HEK293T cells, with IC50 values of 0.50 μM and 0.57 μM, respectively[1].
CAS Number
1831135-30-8
Product Name Alternative
AG-013736
UNSPSC
12352005
Target
Androgen Receptor; MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/jjh260.html
Concentration
10mM
Purity
98.05
Solubility
DMSO : 6.25 mg/mL (ultrasonic)
Smiles
CN(C1=CC=C(C(N2CCN(C3C2)C(N(C3=O)OC(N4CCC(CC4)CCC5=CC=C(C=C5)Cl)=O)=O)=O)C=C1)C
Molecular Formula
C29H34ClN5O5
Molecular Weight
568.06
References & Citations
[1]William H Parsons, et al. AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nat Chem Biol. 2016 May;12 (5) :367-372.|[2]Xinkang Wang, et al. Antithrombotic Effects of the Novel Small-Molecule Factor XIa Inhibitor Milvexian in a Rabbit Arteriovenous Shunt Model of Venous Thrombosis. TH Open. 2023 Apr; 7 (2) : e97–e104.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5802644JJH260

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