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PRMT6-IN-2

CAT: 0804-HY-136809Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-136809Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PRMT6-IN-2 (compound 2) is a dual inhibitor of protein arginine methyltransferase PRMT6 and CARM1 with an IC50 of 30 nM. PRMT6 is abnormally expressed in many cancer cells, and PRMT6-IN-2-based derivatives have potential anticancer activity.
CAS Number
912970-79-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt6-in-2.html
Smiles
CNCCN1CCC(C2=CC3=C(NC(C4=CC=CC=C4OC)=C3F)C=C2)CC1
Molecular Formula
C23H28FN3O
Molecular Weight
381.49
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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