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Recombinant Myoglobin Antibody

CAT: 0013-GTR18574869Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18574869Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia.In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions.
UniProt
P02144
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human full-length protein was used as the immunogen for this recombinant Myoglobin antibody.
Clonality
Recombinant
Clone
RMB/2105
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant Myoglobin antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P02144

Myoglobin

MYG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02144
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q52H51, Q5THY7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cytoplasm

Disease

Disease variant

Ligand

HemeIronMetal-binding

Molecular function

Muscle proteinOxidoreductase

Biological process

Oxygen transportTransport

PTM

Phosphoprotein

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