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Embusartan

CAT: 0804-HY-121313Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121313Size:1 Each
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Description
Embusartan (BAY 10-6734) is a brain-penetrant and effective AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension[1].
CAS Number
156001-18-2
Product Name Alternative
BAY 10-6734
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/embusartan.html
Smiles
O=C(C(C=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2F)=CC1=O)OC
Molecular Formula
C25H24FN5O3
Molecular Weight
461.49
References & Citations
[1]Wang JM, et al. Central nervous system blockade by peripheral administration of AT1 receptor blockers. J Cardiovasc Pharmacol. 2003 Apr;41 (4) :593-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19194578-01Embusartan

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