N-Myristoyl-Lys-Arg-Thr-Leu-Arg

N-Myristoyl-Lys-Arg-Thr-Leu-Arg

• CAS Number: 125678-68-4
• UNSPSC Description: N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
• Target Antigen: PKC
• Type: Peptides
• Related Pathways: Epigenetics;TGF-beta/Smad
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/n-myristoyl-lys-arg-thr-leu-arg.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC(CCCCCCCCCCCCC)=O)=O
• Molecular Weight: 883.18
• References & Citations: [1]Ioannides CG, et, al. Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C. Cell Immunol. 1990 Nov;131(1):242-52.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported