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Bamadutide

CAT: 0804-HY-P10018-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10018-01Size:1 mg
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Description
Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor (GLP-1R/GCGR) agonist. Bamadutide improves post-meal blood glucose control by significantly enhancing β-cell function and slowing down the rate of glucose absorption in the body. Bamadutide can be used for the research of metabolic diseases such as type 2 diabetes[1][2][3].
CAS Number
1596343-09-7
Product Name Alternative
SAR425899
UNSPSC
12352209
Target
GCGR; GLP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bamadutide.html
Purity
99.96
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OC[C@@H](C(N)=O)NC([C@H]1N(C([C@H]2N(C([C@H]3N(C([C@H](C)NC(CNC([C@H](CO)NC([C@H](CO)NC([C@H]4N(C(CNC(CNC([C@H](C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CCC(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CC7=CC=CC=C7)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H](CCCCNC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCC)=O)=O)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@H](CC8=CC=CC=C8)NC([C@H]([C@H](O)C)NC(CNC([C@H](CCC(N)=O)NC([C@@H](CO)NC([C@H](CC9=CNC=N9)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)CCC3)=O)CCC2)=O)CCC1)=O
Molecular Formula
C200H313N51O63
Molecular Weight
4439.93
References & Citations
[1]Olof Eriksson, et al.Imaging of the Glucagon Receptor in Subjects with Type 2 Diabetes.J Nucl Med.2021 Jun 1;62 (6) :833-838.|[2]Visentin R, et al. Dual glucagon-like peptide-1 receptor/glucagon receptor agonist SAR425899 improves beta-cell function in type 2 diabetes. Diabetes Obes Metab. 2020 Apr;22 (4) :640-647.|[3]Xianxing J, et al. Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications. US20230183310A1. 2023-06-15.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2

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CatalogName
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