Hydroxy-PEG4-acid

• Product Name Alternative:

  2-APV; DL-2-Amino-5-phosphonovaleric acid

• UNSPSC Description:

  Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-peg4-acid.html

• Purity:

  97.0

• Solubility:

  DMSO : 200 mg/mL (ultrasonic)|Ethanol : ≥ 200 mg/mL

• Smiles:

  OC(CCOCCOCCOCCOCCO)=O

• Molecular Weight:

  266.29

• References & Citations:

  [1]Tinya Abrams, et al. Antibody drug conjugates. WO2016203432A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  937188-59-5