L-Glutamine-1,2-13C2

• UNSPSC Description:

  L-Glutamine-1,2-13C2 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

• Target Antigen:

  Endogenous Metabolite; Ferroptosis; Isotope-Labeled Compounds; mGluR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Apoptosis;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling;Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-glutamine-1-2-13c2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC(CC[13C@H](N)[13C](O)=O)=O

• Molecular Weight:

  148.13

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Mary Corless , et al. Glutamine Regulates Expression of Key Transcription Factor, Signal Transduction, Metabolic Gene, and Protein Expression in a Clonal Pancreatic Beta-Cell Line. J Endocrinol. 2006 Sep;190(3):719-27.|[3]Newsholme P, et al. Glutamine and glutamate as vital metabolites. Braz J Med Biol Res. 2003 Feb;36(2):153-63. Epub 2003 Jan 29.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported