Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2

• CAS Number: 130877-92-8
• UNSPSC Description: Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity[1].
• Target Antigen: HIV Protease
• Type: Peptides
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/arg-val-nle-p-nitro-phe-glu-ala-nle-nh2.html
• Solubility: 10 mM in DMSO
• Smiles: O=[N+]([O-])C(C=C1)=CC=C1C[C@H](NC([C@H](CCCC)NC([C@H](C(C)C)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N)=O)CCCC)=O)=O)=O
• Molecular Weight: 891.03
• References & Citations: [1]Schramm HJ, et, al. Lipopeptides as dimerization inhibitors of HIV-1 protease. Biol Chem. 1999 May;380(5):593-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported