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FSH-beta Antibody

CAT: 0013-GTR18574007Size: 7 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18574007Size:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
UniProt
P01225
Reactivity
Human
Immunogen
Recombinant hFSH beta subunit was used as the immunogen for the FSH-beta antibody. It does not cross-react with the alpha subunit
Clonality
Monoclonal
Clone
FLTPb-1
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the FSH-beta antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG1, kappa

UniProtKB · P01225

Follitropin subunit beta

FSHB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01225
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FSHB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A2TF08, A5JVV3, Q14D61
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Disease

Disease variantHypogonadotropic hypogonadism

PTM

Disulfide bondGlycoprotein

Molecular function

Hormone

Cellular component

Secreted

Domain

Signal

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