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Progesterone Receptor Antibody

CAT: 0013-GTR18573948Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573948Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) . Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.
Reactivity
Human
Immunogen
Recombinant human Progesterone Receptor protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
PGSR17
Conjugation
Unconjugated
Field of Research
Pharmacology & Drug Discovery
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Progesterone Receptor antibody to be titered up or down for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

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