Products for Research Use Only

C-Myc Antibody

CAT: 0013-GTR18573916Size: 7 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18573916Size:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. [UniProt]
UniProt
P01106
Reactivity
Human
Immunogen
A C-terminal peptide was used as the immunogen for the c-Myc antibody.
Clonality
Monoclonal
Clone
MVH39-1
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Protein G affinity chromatography
Dilution
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Titering of the c-Myc antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG1, kappa

UniProtKB · P01106

Myc proto-oncogene protein

MYC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01106
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A024R9L7, A0A087WUS5, A8WFE7, H0YBT0, P01107, Q14026
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Cellular component

ChromosomeCytoplasmNucleus

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation