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AURKB Antibody / Aurora B

CAT: 0013-GTR18573807Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18573807Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]
UniProt
Q96GD4
Reactivity
Human
Immunogen
Amino acids 89-251 were used as the immunogen for this AURKB antibody.
Clonality
Monoclonal
Clone
ARRK2-1
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Protein G affinity
Dilution
IHC (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the AURKB antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1

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