Products for Research Use Only
RegisterLogin

Recombinant CFTR Antibody

CAT: 0013-GTR18573447Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18573447Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CFTR functions as an ATP-gated anion channel, increasing the conductance for certain anions (e.g. Cl−) to flow down their electrochemical gradient. ATP-driven conformational changes in CFTR open and close a gate to allow transmembrane flow of anions down their electrochemical gradient.[5] This in contrast to other ABC proteins, in which ATP-driven conformational changes fuel uphill substrate transport across cellular membranes. Essentially, CFTR is an ion channel that evolved as a 'broken' ABC transporter that leaks when in open conformation. CFTR is found in the epithelial cells of many organs including the lung, liver, pancreas, digestive tract, and the reproductive tract. [Wiki]
UniProt
P13569
Reactivity
Human
Immunogen
A recombinant human partial protein was used as the immunogen for this recombinant CFTR antibody.
Clonality
Recombinant
Clone
RCFTR/1342
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein G affinity chromatography
Dilution
Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant CFTR antibody should be determined by the researcher. 1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

Related Products

CatalogName
GTR18573303CFTR Antibody
GTR18581654-01CFTR Antibody
GTR18197102-01CFTR Antibody
GTR18193944-01CFTR Antibody
GTR18193943-01CFTR Antibody
GTR18193525-01CFTR Antibody
GTR18192227-01CFTR Antibody
GTR18405794-01CFTR Antibody
GTR18128993CFTR Antibody
GTR18128844CFTR Antibody

Alternative Products

CatalogName
33-787Recombinant CFTR Antibody [CFTR/1775R]
MBS566826-01CFTR Recombinant monoclonal antibody (CFTR/1775R)
V3552SAF-100UGRecombinant CFTR Antibody
V3441-100UGRecombinant CFTR Antibody / Rabbit Monoclonal
HA723168CFTR Recombinant Rabbit monoclonal Antibody
V5476-100UGRecombinant CFTR Antibody / Cystic Fibrosis Transmembrane Regulator
V9549SAF-100UGRecombinant Cystic Fibrosis Transmembrane Regulator Antibody / CFTR
MBS4381762-01CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) Recombinant Rabbit Monoclonal Antibody [Clone CFTR/7003R]
12-1015-100Recombinant Rabbit Monoclonal Antibody to CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (Clone : CFTR/1775R)
33-786CFTR Antibody [CFTR/1785]

Popular Products