Products for Research Use Only
RegisterLogin

Desmin Antibody

CAT: 0013-GTR18573159Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18573159Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
UniProt
P17661
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human Desmin was used as the immunogen for the Desmin antibody.
Clonality
Monoclonal
Clone
DES/1711
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
Immunofluorescence: 1-2ug/ml, Flow cytometry: 0.5-1ug/10^6 cells, Western blot: 0.5-1ug/ml, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Desmin antibody should be determined by the researcher.
Tested Applications
FACS, IF, IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

Related Products

CatalogName
GTR19016976-01Desmin
GTR19016977-01Desmin
GTR19016922-01Desmin
GTR19017534-01Desmin
GTR19017015-01Desmin
GTR19016899-01Desmin
GTR18290585-01Desmin monoclonal antibody
GTR18283321Desmin Conjugated Antibody
GTR18043950-01Desmin polyclonal antibody
GTR18198539Desmin Polyclonal Antibody

Alternative Products

CatalogName
10R-7986Desmin antibody
GWB-74D3ACDesmin, Antibody

Popular Products