Products for Research Use Only
RegisterLogin

CD34 Antibody

CAT: 0013-GTR18572906Size: 7 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18572906Size:7 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens) . Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
UniProt
P28906
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the CD34 antibody.
Clonality
Monoclonal
Clone
SPM610
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein G affinity chromatography
Dilution
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD34 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
Isotype
Mouse IgG1, kappa

Related Products

CatalogName
GTR18594635-01CD34 Biosimilar (ITRI patent CD34 Reference Antibody)
GTR18212799-01CD34 monoclonal antibody
GTR18047857-01CD34 polyclonal antibody
GTR18064874-01CD34 Polyclonal Antibody
GTR18311717-01CD34 Reference Antibody
GTR18288408CD34 Conjugated Antibody
GTR17698627CD34-T Antibody
GTR18207264-01CD34 PAT3B6AT Antibody
GTR18272882CD34 Conjugated Antibody
GTR18048782-01CD34 Polyclonal Antibody

Alternative Products

CatalogName
V0023-01CD34 (ABT-CD34) Antibody
ABP-PAB-00010CD34 antigen (CD34) polyclonal antibody
MBS9510628-01Anti-CD34 Antibody [ABT-CD34]
10R-2342CD34 antibody
GWB-E7146DCD34, Antibody
244369CD34 (CD34 Molecule)

Popular Products