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CD46 Antibody

CAT: 0013-GTR18571779Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18571779Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.
UniProt
P15529
Reactivity
Human
Immunogen
Recombinant human CD46 protein was used as the immunogen for the CD46 antibody.
Clonality
Monoclonal
Clone
197-2B1
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein affinity
Dilution
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CD46 antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2a, kappa

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