Products for Research Use Only
RegisterLogin

NOC4L Antibody

CAT: 0013-GTR18571572Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18571572Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
UniProt
Q9BVI4
Reactivity
Human
Immunogen
Recombinant full-length human NOC4L protein was used as the immunogen for the NOC4L antibody.
Clonality
Monoclonal
Clone
PCRP-NOC4L-1B2
Conjugation
Unconjugated
Purification
Protein A/G affinity
Dilution
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the NOC4L antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1

UniProtKB · Q9BVI4

Nucleolar complex protein 4 homolog

NOC4L_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9BVI4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOC4L
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
NOC4 protein homolog
EC number
—
Processing
—
Secondary accessions
Q8N2S5, Q96I14
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

CytoplasmEndosomeMembraneNucleus

Biological process

Ribosome biogenesis

Domain

TransmembraneTransmembrane helix

Related Products

CatalogName
GTR18201588NOC4L Polyclonal Antibody
GTR18046370-01NOC4L polyclonal antibody
GTR19057354NOC4L Peptide
GTR17868782NOC4L Rabbit Polyclonal Antibody
GTR18035739-01NOC4L Rabbit Polyclonal Antibody
GTR18098661NOC4L Rabbit Polyclonal Antibody
GTR17868783NOC4L Rabbit Polyclonal Antibody
GTR18308570NOC4L Rabbit Polyclonal Antibody
GTR18700995-01NOC4L Rabbit Polyclonal Antibody
GTR18095958NOC4L Rabbit Polyclonal Antibody

Alternative Products

CatalogName
V9358SAF-100UGNOC4L Antibody
NBP3-13798-20ugMouse Monoclonal NOC4L Antibody (PCRP-NOC4L-1B2)
NBP3-07362-20ugMouse Monoclonal NOC4L Antibody (PCRP-NOC4L-1E3)
526047-01NOC4L

Popular Products