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Interferon gamma Antibody / IFNG

CAT: 0013-GTR18572190Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18572190Size:100 µg
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Description
Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-g and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-g. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts.
UniProt
P01579
Reactivity
Human
Immunogen
A recombinant fragment (within amino acids 1-166) of human IFNG protein was used as the immunogen for the Interferon gamma antibody.
Clonality
Monoclonal
Clone
IFNG/9012
Conjugation
Unconjugated
Field of Research
Infectious Disease & Virology; Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Interferon gamma antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P01579

Interferon gamma

IFNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma
EC number
—
Processing
Precursor
Secondary accessions
B5BU88, Q53ZV4
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Antiviral defenseGrowth regulation

PTM

Cleavage on pair of basic residuesGlycoproteinPyrrolidone carboxylic acid

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal

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