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Recombinant PAX7 Antibody

CAT: 0013-GTR18571503-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18571503-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma) .
UniProt
P23759
Reactivity
Human
Immunogen
A recombinant fragment (amino acids 301-505) of human PAX7 protein was used as the immunogen for the recombinant PAX7 antibody.
Clonality
Recombinant
Clone
RPAX7/9325
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant PAX7 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG2b, kappa

UniProtKB · P23759

Paired box protein Pax-7

PAX7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23759
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAX7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E9PFV9, Q0VA99, Q2PJS5
Protein keywords

PTM

Acetylation

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Molecular function

Developmental proteinDNA-binding

Disease

Disease variantProto-oncogene

Domain

HomeoboxPaired box

Biological process

MyogenesisTranscriptionTranscription regulation

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

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