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KLF12 Antibody

CAT: 0013-GTR18571175Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18571175Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
UniProt
Q9Y4X4
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the KLF12 antibody.
Clonality
Monoclonal
Clone
PCRP-KLF12-1E3
Conjugation
Unconjugated
Purification
Protein A/G affinity
Dilution
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the KLF12 antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1

UniProtKB · Q9Y4X4

Krueppel-like factor 12

KLF12_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y4X4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KLF12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K5T2, L0R3J4, Q5VZM7, Q9UHZ0
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

DNA-bindingRepressor

Ligand

Metal-bindingZinc

PTM

MethylationPhosphoprotein

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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