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Saintopin

CAT: 0804-HY-120185Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120185Size:1 Each
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Description
Saintopin is an antitumor antibiotic. Saintopin is also an inhibitor of DNA topoisomerases I and II. Saintopin induces DNA cleavage[1][2].
CAS Number
131190-63-1
Product Name Alternative
UCT-1003
UNSPSC
12352005
Target
Antibiotic; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/saintopin.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(O)=CC(O)=C1C2=O)C3=C2C(O)=C4C(O)=CC(O)=CC4=C3
Molecular Formula
C18H10O7
Molecular Weight
338.27
References & Citations
[1]Yamashita Y, et al. Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces. J Antibiot (Tokyo) . 1990 Oct;43 (10) :1344-6.|[2]eteurtre F, et al. Saintopin, a dual inhibitor of DNA topoisomerases I and II, as a probe for drug-enzyme interactions. J Biol Chem. 1994 Nov 18;269 (46) :28702-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo I; Topo II

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