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Dirucotide

CAT: 0804-HY-P3541Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3541Size:1 Each
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Description
Dirucotide (MBP8298) is a synthetic peptide that consists of 17 amino acids linked in a sequence identical to that of a portion of human myelin basic protein. Dirucotide can be used for the research in autoimmune disorder of the central nervous system, such as Multiple sclerosis (MS) [1].
CAS Number
152074-97-0
Product Name Alternative
MBP8298
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dirucotide.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C92H141N25O26
Molecular Weight
2013.25
References & Citations
[1]Leslie Boudesocque, et al. Purification of dirucotide, a synthetic 17-aminoacid peptide, by ion exchange centrifugal partition chromatography. J Chromatogr A. 2017 Sep 1;1513:78-83.|[2]Hubert Kalbacher, et al. Design of Linear and Cyclic Mutant Analogues of Dirucotide Peptide (MBP82⁻98) against Multiple Sclerosis: Conformational and Binding Studies to MHC Class II. Brain Sci. 2018 Dec 4;8 (12) :213.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 3

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