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ADAR1 Rabbit Polyclonal Antibody (APC)

CAT: 0013-GTR18562928Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18562928Size:100 µg
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Description
ADAR1 Rabbit Polyclonal Antibody (APC)
Product Name Alternative
Double-stranded RNA-specific adenosine deaminase; DRADA; 3.5.4.37; 136 kDa double-stranded RNA-binding protein; p136; Interferon-inducible protein 4; IFI-4; K88DSRBP; ADAR; ADAR1, DSRAD, G1P1, IFI4
UniProt
P55265
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
E.coli-derived human ADAR1 recombinant protein (Position: S128-Q346) . Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively.
Target
Double-stranded RNA-specific adenosine deaminase
Clonality
Polyclonal
Conjugation
APC
Field of Research
Epigenetics & Chromatin, Infectious Disease & Virology, Microbiology, Molecular Biology
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
136066 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · P55265

Double-stranded RNA-specific adenosine deaminase

DSRAD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55265
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ADAR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DRADA
EC number
3.5.4.37
Processing
—
Secondary accessions
B1AQQ9, B1AQR0, D3DV76, O15223, O43859, O43860, Q9BYM3, Q9BYM4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Aicardi-Goutieres syndromeDisease variant

Coding sequence diversity

Alternative promoter usageAlternative splicing

Biological process

Antiviral defenseImmunityInnate immunitymRNA processingRNA-mediated gene silencing

Cellular component

CytoplasmNucleus

Molecular function

DNA-bindingHydrolaseRNA-binding

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Domain

Repeat

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