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BRCA1 Rabbit Polyclonal Antibody (Biotin)

CAT: 0013-GTR18561737Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18561737Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-BRCA1 Antibody. Tested in ICC, IF, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Name Alternative
Breast cancer type 1 susceptibility protein; 6.3.2.-; RING finger protein 53; BRCA1; RNF53
UniProt
P38398
Reactivity
Human, Mouse, Rat
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
E.coli-derived human BRCA1 recombinant protein (Position: T1681-E1781) . Human BRCA1 shares 73.3% and 74.3% amino acid (aa) sequence identity with mouse and rat BRCA1, respectively.
Target
Breast cancer type 1 susceptibility protein
Clonality
Polyclonal
Conjugation
Biotin
Field of Research
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry, Signal Transduction
Purification
Immunogen affinity purified.
Dilution
Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
207721 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
Notes
For research use only.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · P38398

Breast cancer type 1 susceptibility protein

BRCA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
E9PFZ0, O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingTransferase

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cell cycleDNA damageDNA recombinationDNA repairTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantFanconi anemiaTumor suppressor

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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