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ErbB 2/ERBB2 Rabbit Polyclonal Antibody (PE)

CAT: 0013-GTR18561336Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18561336Size:100 µg
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Description
ErbB 2/ERBB2 Rabbit Polyclonal Antibody (PE)
Product Name Alternative
Receptor tyrosine-protein kinase erbB-2; 2.7.10.1; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340; ERBB2; HER2, MLN19, NEU, NGL
UniProt
P04626
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ErbB 2, identical to the related mouse and rat sequences.
Target
Receptor tyrosine-protein kinase erbB-2
Clonality
Polyclonal
Conjugation
PE
Field of Research
Cancer Biology, Cell Biology, Disease Biomarkers, Protein Biochemistry, Signal Transduction
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Molecular Weight
137910 Da
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · P04626

Receptor tyrosine-protein kinase erbB-2

ERBB2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P04626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERBB2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorKinaseReceptorTransferaseTyrosine-protein kinase

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCell projectionCytoplasmEndosomeMembraneNucleus

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Biological process

TranscriptionTranscription regulation

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