Arteannuin B

CAT: 0804-HY-N2016-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N2016-01Size:5 mg
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Description
Arteannuin B, No. 2000 can be jointly submitted with the blue material. Arteannuin B had anti-SARS-CoV-2 activity, EC50=10.28 μM[1][2][3].
CAS Number
[50906-56-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ferroptosis; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/arteannuin-b.html
Purity
99.89
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C[C@@]1(CC[C@]2([H])[C@@]3(OC4=O)[C@](CC[C@H]2C)([H])C4=C)[C@H]3O1
Molecular Formula
C15H20O3
Molecular Weight
248.32
Precautions
H302, H315, H319, H335
References & Citations
[1]Ruiyuan Cao, et al. Anti-SARS-CoV-2 Potential of Artemisinins In Vitro. RETURN TO JUST ACCEPTED MANUSCRIPTS.|[2]Nair MS, et al. Bioconversion of arteannuin B to artemisinin. J Nat Prod. 1993 Sep;56 (9) :1559-66.|[3]Varela K, et al. Inhibition of Cysteine Proteases via Thiol-Michael Addition Explains the Anti-SARS-CoV-2 and Bioactive Properties of Arteannuin B. J Nat Prod. 2023 Jul 28;86 (7) :1654-1666.|[4]Huang W, et al. Arteannuin B Enhances the Effectiveness of Cisplatin in Non-Small Cell Lung Cancer by Regulating Connexin 43 and MAPK Pathway. Am J Chin Med. 2022;50 (7) :1963-1992.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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