Arteannuin B

• Description :

  Arteannuin B, No. 2000 can be jointly submitted with the blue material. Arteannuin B had anti-SARS-CoV-2 activity, EC50=10.28 μM[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Ferroptosis; SARS-CoV

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/arteannuin-b.html

• Purity :

  99.89

• Solubility :

  DMSO : 25 mg/mL (ultrasonic)

• Smiles :

  C[C@@]1(CC[C@]2([H])[C@@]3(OC4=O)[C@](CC[C@H]2C)([H])C4=C)[C@H]3O1

• Molecular Formula :

  C15H20O3

• Molecular Weight :

  248.32

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Ruiyuan Cao, et al. Anti-SARS-CoV-2 Potential of Artemisinins In Vitro. RETURN TO JUST ACCEPTED MANUSCRIPTS.|[2]Nair MS, et al. Bioconversion of arteannuin B to artemisinin. J Nat Prod. 1993 Sep;56 (9) :1559-66.|[3]Varela K, et al. Inhibition of Cysteine Proteases via Thiol-Michael Addition Explains the Anti-SARS-CoV-2 and Bioactive Properties of Arteannuin B. J Nat Prod. 2023 Jul 28;86 (7) :1654-1666.|[4]Huang W, et al. Arteannuin B Enhances the Effectiveness of Cisplatin in Non-Small Cell Lung Cancer by Regulating Connexin 43 and MAPK Pathway. Am J Chin Med. 2022;50 (7) :1963-1992.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [50906-56-4]