Products for Research Use Only

Tiopronin

CAT: 0804-HY-B0373-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0373-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders[1][2].
CAS Number
1953-02-2
UNSPSC
12352211
Hazard Statement
H302
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Tiopronin.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CNC(C(S)C)=O
Molecular Formula
C5H9NO3S
Molecular Weight
163.20
Precautions
H302
References & Citations
[1]Pu Zhang, et al. Detection of tiopronin in body fluids and pharmaceutical products using red-emissive DNA-stabilized silver nanoclusters as a fluorescent probe. Mikrochim Acta. 2019 Aug 8;186 (9) :609.|[2]Soohwan Yum, et al. N- (2-Mercaptopropionyl) -glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant. Biochem Biophys Res Commun. 2014 Jan 17;443 (3) :1008-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched