Cl-C6-PEG4-O-CH2COOH

• UNSPSC Description:

  Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is a PEG-based PROTAC linker can be used in the synthesis of chloroalkane-containing PROTACs (HaloPROTACs)[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/PROTAC_Linker_4.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)

• Smiles:

  ClCCCCCCOCCOCCOCCOCCOCC(O)=O

• Molecular Weight:

  370.87

• References & Citations:

  [1]Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1799506-30-1