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APP/C99 Rabbit Polyclonal Antibody (PE)

CAT: 0013-GTR18556587Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18556587Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-APP/C99 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
Product Name Alternative
ABETA; ABPP; amyloid beta 1-42; Amyloid beta A4 protein; amyloid P; amyloid precursor protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; APP; APPI; Aβ1-42; beta Amyloid
UniProt
P05067
Reactivity
Human
Cross Reactivity
No cross-reactivity with other proteins.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human APP/C99.
Target
Amyloid-beta precursor protein
Clonality
Polyclonal
Conjugation
PE
Field of Research
Cell Biology, Neuroscience, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purification
Immunogen affinity purified.
Dilution
Optimal dilutions should be determined by end users.
Form
Liquid
Storage Conditions
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Notes
For research use only.
Applications Notes
Recommended applications are based on the parent unconjugated antibody. Customers may select suitable applications according to their experimental needs.
Host or Source
Rabbit
Preservative
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Isotype
Rabbit IgG

UniProtKB · P05067

Amyloid-beta precursor protein

A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P05067
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
APP
EC number
—
Processing
Precursor
Secondary accessions
B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q6GSC0, Q8WZ99, Q9BT38, Q9UC33, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

AmyloidCell membraneCell projectionCoated pitCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Biological process

ApoptosisCell adhesionEndocytosisNotch signaling pathway

Ligand

CopperIronMetal-bindingZinc

PTM

Disulfide bondGlycoproteinIsopeptide bondOxidationPhosphoproteinProteoglycanSulfationUbl conjugation

Molecular function

Heparin-bindingProtease inhibitorSerine protease inhibitor

Domain

SignalTransmembraneTransmembrane helix

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