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Pyridaben

CAT: 0804-HY-B0817-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0817-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyridaben is a mitochondrial electron transport inhibitor (METI) acaricide that promotes the formation of damaging oxygen and nitrogen radicals. Pyridaben selectively inhibits complex I (NADH dehydrogenase) with an IC50 value of 2.4 nM (assay sites: rat liver and bovine heart mitochondria) . Pyridaben also significantly inhibits rat mitochondrial mtNOS function[1][2].
CAS Number
96489-71-3
UNSPSC
12352005
Hazard Statement
H301+H331-H410
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pyridaben.html
Concentration
10mM
Purity
99.27
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(Cl)=C(SCC2=CC=C(C(C)(C)C)C=C2)C=NN1C(C)(C)C
Molecular Formula
C19H25ClN2OS
Molecular Weight
364.93
Precautions
P261-P264-P270-P271-P273-P304+P340-P330-P391-P403+P233-P405-P501
References & Citations
[1]Gomez C, et al. Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome. Front Biosci. 2007 Jan 1;12:1079-93. |[2]Namin HH, et al. Resistance to pyridaben in Canadian greenhouse populations of two-spotted spider mites, Tetranychus urticae (Koch) . Pestic Biochem Physiol. 2020 Nov;170:104677.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Mite

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