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GZ4

CAT: 0804-HY-135228Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-135228Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GZ4 is a calcium current inhibitor with direct inhibitory activity on cell surface channels. GZ4 inhibition reverses mechanical hyperalgesia/hyperalgesia in a spinal nerve ligation-induced neuropathic pain model. The mechanism of action of GZ4 is similar to that of gabapentin, but the time course of its biological effects is more rapid, indicating that GZ4 can directly inhibit calcium channel currents[1].
CAS Number
68312-88-9
UNSPSC
12352211
Hazard Statement
H302-H312-H332
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gz4.html
Smiles
O=C(C12CC3CC(C2)CC(C1N)C3)O
Molecular Formula
C11H17NO2
Molecular Weight
195.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Anti-allodynic effect of 2- (aminomethyl) adamantane-1-carboxylic acid in a rat model of neuropathic pain: a mechanism dependent on CaV2.2 channel inhibition
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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