Glufosinate

• Description:

  Glufosinate, a phosphinic acid analogue of glutamic acid, is a herbicide which is converted by plant cells into PT (L-phosphinothricin) . Glufosinate exerts neurotoxic activity[1][2].

• UNSPSC:

  12352211

• Hazard Statement:

  H302-H312-H332-H361-H370-H373-H400-H410

• Target:

  Herbicide

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/glufosinate.html

• Purity:

  90.00

• Solubility:

  10 mM in DMSO

• Smiles:

  CP(O)(CCC(N)C(O)=O)=O

• Molecular Formula:

  C5H12NO4P

• Molecular Weight:

  181.13

• Precautions:

  P260-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P363-P391-P405-P501

• References & Citations:

  [1]Áy Z, et al. The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. ScientificWorldJournal. 2012;2012:657945.|[2]Feat-Vetel J, et al. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology. 2018 Dec;69:152-163.|[3]Ebert E, et al. Summary of safety evaluation toxicity studies of glufosinate ammonium. Food Chem Toxicol. 1990 May;28 (5) :339-49.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [51276-47-2]