Thiocolchicoside

• Description :

  Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H301-H341-H361-H372

• Target :

  GABA Receptor

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/thiocolchicoside.html

• Purity :

  99.54

• Solubility :

  DMSO : 233.33 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

• Smiles :

  CSC1=CC=C2C3=C(OC)C(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3CC[C@H](NC(C)=O)C2=CC1=O

• Molecular Formula :

  C27H33NO10S

• Molecular Weight :

  563.62

• Precautions :

  P260-P264-P270-P280-P330-P405-P501

• References & Citations :

  A

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [602-41-5]