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YS07

CAT: 0804-HY-162509Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162509Size:1 Each
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Description
YS07 is a potent VEGFR-2 inhibitor. Molecular dynamics simulation study revealed sustained interactions of YS07 with key amino acids of VEGFR-2 at a run time of 100 ns. YS07 can be used for anticancer research[1].
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ys07.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC(C=CC=C2)=C2N1)CNC3=CC=C(C=C3)C4=NC5=CC=CC=C5N4
Molecular Formula
C22H18N6O
Molecular Weight
382.42
References & Citations
[1]Gupta S, et al. In silico insights into design of novel VEGFR-2 inhibitors: SMILES-based QSAR modelling, and docking studies on substituted benzo-fused heteronuclear derivatives. SAR QSAR Environ Res. 2024 Apr;35 (4) :265-284.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1

Alternative Products

CatalogName
T210120-01YS07

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