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Q134R

CAT: 0804-HY-139464-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139464-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research[1].
CAS Number
2022949-46-6
UNSPSC
12352005
Target
Nuclear Factor of activated T Cells (NFAT)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/q134r.html
Purity
99.55
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(N=CC=C2)C2=CC=C1[C@@H](C3=CC=C(C(F)(F)F)C=C3)NC4=NC=CC(C)=N4
Molecular Formula
C22H17F3N4O
Molecular Weight
410.39
References & Citations
[1]Pradoldej Sompol, et al. Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology. Aging Cell. 2021 Jul;20 (7) :e13416.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
MBS5784956Q134R

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