NH2-PEG6-Boc

• UNSPSC Description:

  NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

• Target Antigen:

  ADC Linker; PROTAC Linkers

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nh2-peg6-boc.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCN

• Molecular Weight:

  409.51

• References & Citations:

  [1]Foley CA, et al. Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay. ACS Chem Biol. 2020 Jan 17;15(1):290-295.|[2]Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1286281-32-0