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Ligustilide

CAT: 0804-HY-N0401-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0401-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects[1][2][3].
CAS Number
4431-01-0
UNSPSC
12352005
Hazard Statement
H301
Target
Apoptosis; Autophagy
Type
Natural Products
Related Pathways
Apoptosis; Autophagy
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Ligustilide.html
Purity
99.17
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1O/C(C2=C1C=CCC2)=C\CCC
Molecular Formula
C12H14O2
Molecular Weight
190.24
Precautions
H301
References & Citations
[1]Wu Q, et al. Protective effect of ligustilide against glutamate-induced apoptosis in PC12 cells. Yao Xue Xue Bao. 2015 Feb;50 (2) :162-8.|[2]Jing Ma, et al. Ligustilide promotes apoptosis of cancer-associated fibroblasts via the TLR4 pathways. Food Chem Toxicol. 2020 Jan;135:110991.|[3]Eun Sik Choi, et al. Ligustilide attenuates vascular inflammation and activates Nrf2/HO-1 induction and, NO synthesis in HUVECs. Phytomedicine. 2018 Jan 1;38:12-23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Launched

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