Recombinant Mouse Erythroferrone (Erfe)

CAT: 0399-CSB-EP757647MO-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0399-CSB-EP757647MO-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

Complement C1q tumor necrosis factor-related protein 15 Myonectin

Abbreviation

Recombinant Mouse Erfe protein

Gene Name

Erfe

UniProt

Q6PGN1

Expression Region

25-340aa

Organism

Mus musculus (Mouse)

Target Sequence

LGVPESAEPVGTHARPQPPGAELPAPPANSPPEPTIAHAHSVDPRDAWMLFVKQSDKGINSKRRSKARRLKLGLPGPPGPPGPQGPPGPFIPSEVLLKEFQLLLKGAVRQRESHLEHCTRDLTTPASGSPSRVPAAQELDSQDPGALLALLAATLAQGPRAPRVEAAFHCRLRRDVQVDRRALHELGIYYLPEVEGAFHRGPGLNLTSGQYTAPVAGFYALAATLHVALTEQPRKGPTRPRDRLRLLICIQSLCQHNASLETVMGLENSSELFTISVNGVLYLQAGHYTSVFLDNASGSSLTVRSGSHFSAILLGL

Tag

N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged

Type

Developed Protein

Source

E.coli

Field of Research

Others

Relevance

Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake

Endotoxin

Not test

Purity

Greater than 85% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Function

Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage

Molecular Weight

53.9 kDa

References & Citations

"Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis." Seldin M.M., Peterson J.M., Byerly M.S., Wei Z., Wong G.W. J. Biol. Chem. 287:11968-11980 (2012)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Protein Length

Full Length of Mature Protein

UniProtKB · Q6PGN1

Erythroferrone

ERFE_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: Q6PGN1
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Erfe
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: E3VWA0, Q8CE11

Protein keywords

PTM

Disulfide bondGlycoproteinHydroxylation

Molecular function

Hormone

Technical term

Reference proteome

Cellular component

Secreted

Domain

Signal

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Alternative Products

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MBS2123972-01	Recombinant Erythroferrone (ERFE)
MBS1417365-01	Recombinant Mouse Erythroferrone (Erfe)
AP9C224-01	Recombinant Bovine Erythroferrone (ERFE)
AP9C76-01	Recombinant Swine Erythroferrone (ERFE)
RPU56180-01	Recombinant Human Erythroferrone (ERFE)
MBS7111111-01	Recombinant Human Erythroferrone (ERFE), partial
ELK11325-01	Mouse ERFE (Erythroferrone) ELISA Kit
MBS1607973-01	Mouse Erythroferrone, ERFE ELISA Kit
JOT-EK2681Mo-01	Mouse Erythroferrone,ERFE ELISA KIT
AP89512-01	Recombinant Human Erythroferrone(ERFE), partial